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pentobarbital decreases levels of ponatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Steer clear of Unless of course the coadministration outweighs the probable hazard of ponatinib underexposure; keep an eye on for signs of minimized efficacy.pentobarbital will lower the extent or effect of bexarotene b

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